- Haemophilia A
- Haemophilia B
- Haemophilia C
- Acquired haemophilia
(immune system attack the clotting factors in the blood)
- Genetic defect present on the X chromosome.
- Male are more prone to the disease;female being carrier
- Spontaneous genetic mutation
Symptoms And Signs—
- Mild hemophilia —
- Person has 6 percent to 49 percent of the normal factor level
- Bleeds only after serious injury, trauma or surgery
- First episode of bleeding may not occur until adulthood.
2. Moderate hemophilia-
- Person has 1 percent to 5 percent of the normal factor level
- Bleeding episodes after injuries, major trauma or surgery
- Occasional bleeding without obvious cause ( spontaneous bleeding episodes)
3. Severe hemophilia-
- Person has less than 1 percent factor level
- Bleeding following an injury or surgery
- Frequent spontaneous bleeding episodes into the joints and muscles.
- Ache, tingling or irritation in joints (usually in knees, elbows or ankles)
- Pain and swelling in joints
- Large and deep bruises
- Prolonged bleeding after a cut, tooth extraction or surgery
- Blood in urine or faeces
- Bruises on picking(infants)
- Prenatal testing
Chorionic villus sampling (CVS). During CVS, a small sample of placenta (after-birth) is removed from the uterus and tested for the hemophilia gene.
2. Blood tests ( to determine if clotting factors are missing or at low levels)
- Replacement therapy
The replacement clotting factor may come from human blood or genetically engineered to prevent and treat prolonged bleeding. The clotting factors can be given by injection on a regular basis.
- Deep internal bleeding
- Continous bleeding (Development of an antibody to the clotting factor concentrate used to treat or prevent bleeding. This antibody keeps the clotting factor concentrate from working effectively to stop bleeding)
- Joint deformity and destruction
- Regular testing for blood-borne diseases.
- Get Immunized for Hepatitis A and B
- Regular exercise and maintain a healthy weight
- Seeking prompt treatment when bleeding occurs
- Family members should learn to recognize signs of bleeding in children