Causative agent–

Treponema pallidum

Primary stage

  • Chancres appear 21 days after sexual contact with an infected person; On the vulva, cervix (female); On the penis(male)

  • Primary lesion is circular, indurated with an eroded base
  • Marked edema of the surrounding tissues
  • Superficial inguinal lymphadenopathy

Secondary stage

  • Generalized skin eruptions

  • Fever
  • Papulo-squamous lesions
  • Flat, warty-looking growths (vulva –female and around anus -both sexes)
  • White patches on the tongue or roof of the mouth.
  • Patchy hair loss.


  • Lesions my form large plaques and are highly infectious

Latent and tertiary stages

Gummatous lesion of skin/mucous membrane (rarely seen on genitalia)

  • Paralysis
  • Tabes dorsalis
  • Aortic incompetence
  • Insanity



  • Immune-flouroscent technique
  • Flouroscent treponemal antibody absorption test(FTA)
  • VDRL
  • Complement fixation(Wassermann)
  • Spinal fluid test (neurosyphilis)


Early syphilis

Ayurvedic Medicines

Late syphilis

Damage done to body organs cannot be reversed.

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