Filariasis

Causative agents—

  • Wuchereria bancrofti
  • Brugia malayi
  • Brugia timori

Transmission–

By Mosquitoes from person to person. The larvae enter the body at the time of the mosquito bite and travel to the lymphatic system, where they mature into adult worms. The adult worms can live for years in the lymphatic system, and they produce immature forms that circulate in the blood.

Symptoms and Signs–

  • Elephantiasis
  • Swelling of the legs, arms, breasts and genitals
  • Chills and rigors
  • Excessive sweating
  • Headache
  • Pyrexia
  • Muscle aches and pains
  • Nausea with or without vomiting
  • Eosinophilia

Investigations—

  • Blood test CBC
  • Urine test
  • Blood smears

Treatment–

Medicines

Complications–

  • Kidney damage
  • Hydrocele
  • Disfigurement
  • Sexual disability

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