CLL affects lymphoid cells and usually grows slowly. It almost never affects children.
Causes—-
Cause is unknown. There is no link to radiation, cancer-causing chemicals, or viruses.
CLL primarily affects adults. The disease is more common in Jewish people of Russian or East European descent, and is uncommon in Asians.
Symptoms And Signs–
- Breathlessness
- Early satiety
- Loss of appetite
- Night sweats
- Repeated infections
- Swollen lymph nodes
- Swollen spleen
- Tiredness
- Unintentional weight loss
- Unusual bleeding and bruising
- Weakness
Investigations—
- Full blood count
- Bone marrow biopsy
- CT scan-Abdomen,chest,pelvis
- Flow cytometry
- Serum immunoglobin level
- Serum lactate dehydrogenase (LDH) level
Treatment—-
- Chemotherapy
- Radiation(rarely used)
- Blood transfusion
- Bone marrow or stem cell transplantation
Complications—-
- Autoimmune hemolytic anemia
- Hypogammaglobulinemia
- Idiopathic thrombocytopenic purpura (ITP)
- Other cancers
- Side effects of chemotherapy