Rapidly progressive glomerulonephritis

Rapidly progressive glomerulonephritis (RPGN) is a syndrome of the kidney with many of the glomeruli containing characteristic glomerular crescents (crescent-shaped scars). Because of this microscopic feature, RPGN is also called crescentic glomerulonephritis.

 Causes—

  • Goodpasture syndrome
  • Systemic lupus erythematosus
  • Wegener granulomatosis
  • idiopathic

 Signs & Symptoms—

  • Hematuria
  • Rapid loss of renal function
  • Proteinuria
  • Hypertension
  • Edema.

Investigations—

  • Urine tests( protein and red blood cells)
  • kidney biopsy
  • blood culture

Treatment—

  • Ayurvedic Medicines
  • Plasmapharesis( blood filtering)
  • Bed rest
  • Restricted fluid and salt intake

 Complications—

  • Oliguria( poor kidney function)
  • Acute renal failure
  • Death (within months)

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